"Other parts of ancient Eurasia had traditions of third-gender spirit-people. Herodotus and Hippocrates both discuss the “enarees”, or male-to-female transsexual shamans among the ancient Scythians, who “mutilated” their genitalia and took on female roles. They were said to be the most powerful shamans of their people. Ovid actually claimed that some Scythian priestesses knew how to extract “female poison” distilled from the urine of a mare in heat, with which to dose men in order to feminize them. The average person might throw this off as silliness, if they didn’t know that pregnant mare’s urine is the main source of Premarin, the most widely used estrogen drug today. They also ate a lot of licorice root - so popular among them that the Greeks to whom they exported it referred to it as “the Scythian root” - which is also an anti-androgen."